Machine learning, integrated with data generation at scale, lies at the core of insitro’s approach to rethinking drug discovery and development. As Head of Molecular Design you will lead our small molecule medicinal chemistry efforts, helping us transform how drugs are designed, through the use of powerful predictive models, relating molecular structure to drug property, built through machine learning. You will couple these models with new ways of exploring and interrogating drug-like chemical space, achieving unprecedented advances in the speed and scale of hit discovery and lead optimization. You will drive our molecular design across a portfolio of therapeutic programs, delivering a stream of outstanding clinical candidates, and helping advance these into the clinic. You will work closely with world-class machine learning, data engineering, translational science and DNA-encoded library teams to grow our drug design capabilities and scale our therapeutic portfolio. You will partner with therapeutic teams to design and execute research project plans which reflect insitro’s data science-led philosophy for drug discovery. You will have demonstrated your ability to work in a highly cross-disciplinary, fast-moving and fluid environment, and will draw upon extensive experience driving drug discovery projects forward. You will possess strong interpersonal and leadership skills, an ability to lead cross-functionally, a strong collaborative work ethic, ability to adapt to changing needs, and the capacity to multitask to meet key goals. Strong communication and presentation skills are essential to success in this position.
Specifically, you will:
You will be joining the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in formation. Much can change in this early and exciting phase, providing many opportunities for significant impact. You will work closely with an exceptionally talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us, and help make a difference to patients!
Benefits at insitro
insitro is a data-driven drug discovery and development company using machine learning and high-throughput biology to transform the way that drugs are discovered and delivered to patients. The company is applying state-of-the-art technologies from bioengineering to create massive data sets that enable the power of modern machine learning methods to be brought to bear on key bottlenecks in pharmaceutical R&D. The resulting predictive models are used to accelerate target selection, to design and develop effective therapeutics, and to inform clinical strategy. insitro was launched in 2018 with a Series A of $100M funded by top investors including a16z, Arch Venture Partners, Foresite Capital, GV, and Third Rock Ventures.
The company has announced collaborations with Gilead Sciences in the area of NASH (2019) and Bristol Myers Squibb in the area of ALS (2020) and, in mid 2020, completed a Series B financing of $143M including current investors and new investors Canada Pension Plan Investment Board (CPP Investments), T. Rowe Price, BlackRock, Casdin Capital and other leading investors. The company is located in South San Francisco, CA. For more information about insitro, please visit the company’s website at www.insitro.com
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