Senior Manager, Financial Reporting & Technical Accounting

G&A · South San Francisco, California
Department G&A
Employment Type Full-Time

The Opportunity

At insitro, we are combining human biology and machine learning to discover and develop new therapeutics. The heart of our strategy is to produce large data sets that will drive machine learning and yield key biological insights. This strategy requires a seamless, robust, and effective operation that simultaneously spans multiple projects, some partnered and some in-house. 

Reporting to the Controller / VP, Finance, we are seeking a dynamic, detail oriented and versatile Senior Manager, Financial Reporting & Technical Accounting to join our growing Accounting and Finance Team.  In this hands on role, you will be responsible for the preparation of all financial reporting and technical accounting memos and analysis.  Further, you will be responsible for all stock administration, stock based compensation reporting, revenue recognition and other higher risk month-end close related activity.  In addition, you will lead and implement process controls, compliance and maintenance of all accounting policies.  A successful candidate has a strong understanding of US GAAP and reporting and stays current with recent accounting pronouncements.  This role will regularly interact with Legal, HR, Business Development, Program Management, and various members of our Leadership Team. 

Your primary duties will be:

  • Coordinate and prepare all financial reporting
    • Compile financial statements and draft footnote disclosures 
    • Prepare tie-out support and complete all applicable disclosure checklists
    • Manage internal and external review for these documents and ensure all comments are addressed 
  • Lead all technical accounting research and documentation
    • Prepare memos in accordance with relevant accounting standards
    • Prepare accounting analysis to support transaction, including but not limited to, preparation of journal entries and reconciliations
    • Collaborate with key business partners on various business transactions and initiatives to ensure relevant accounting issues are assessed in the decision making process 
  • Partner with the Accounting and Finance Team
    • Responsible for Stock Administration accuracy and timeliness of recording and reporting all equity award activities 
    • Prepare stock-based compensation (ASC 718), revenue (ASC 606) and higher risk journal entries and reconciliations, as needed
    • Assist with monthly financial package reporting and ad hoc reports
    • Develop, document and maintain accounting policies that are US GAAP compliant
    • Assist with the preparation of financial materials and other materials used in presentations to the Board and Leadership Team
  • Lead and implement process controls and compliance 
  • Assist with managing the external auditors including coordinating and leading the prepared by client list
  • Lead and / or assist with finance system implementations 
  • Participate in special projects and perform other related duties as assigned


You will be joining an exciting biotech startup that has long-term stability due to significant funding, yet is very much in formation. A lot can change in this early and exciting phase, providing many opportunities for significant impact across several functions and disciplines. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us in leading the way to better medicines through predictive models by integrating machine learning and biology at scale.

About You

  • Bachelor degree in Business, Finance, Accounting or related field  
  • 6+ years of relevant work experience preferably a mix of Big 4 public accounting and public biotech  
  • Active CPA license
  • Strong understanding of US GAAP and reporting
  • Accounting ERP system experience, preferably in Oracle
  • Experience using Carta or similar equity administration system
  • Advanced Excel skills and ability to work in G-Suite
  • Organized and strong attention to detail with an ability to simultaneously research discrepancies and solve problems
  • Effective communicator with good verbal and written communication skills
  • Excellent project management skills and the ability to collaborate with cross-functional leaders and others in the company
  • Ability to work independently with general direction and guidance
  • Ability to prioritize and multitask in an ever changing environment
  • Passion for making a difference in the world


Benefits at insitro

  • Excellent medical, dental, and vision coverage
  • Open vacation policy
  • Team lunches (catered daily)
  • Commuter benefits
  • Paid parental leave


About insitro

insitro is a data-driven drug discovery and development company using machine learning and high-throughput biology to transform the way that drugs are discovered and delivered to patients. The company is applying state-of-the-art technologies from bioengineering to create massive data sets that enable the power of modern machine learning methods to be brought to bear on key bottlenecks in pharmaceutical R&D. The resulting predictive models are used to accelerate target selection, to design and develop effective therapeutics, and to inform clinical strategy. insitro was launched in 2018 with a Series A of $100M funded by top investors including a16z, Arch Venture Partners, Foresite Capital, GV, and Third Rock Ventures. In 2019 the company announced a collaboration with Gilead Sciences in the area of NASH and, in mid 2020, announced a Series B financing of $143M including current investors and new investors Canada Pension Plan Investment Board (CPP Investments), T. Rowe Price, BlackRock, Casdin Capital and other leading investors. The company is located in South San Francisco, CA. For more information about insitro, please visit the company’s website at


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  • Location
    South San Francisco, California
  • Department
  • Employment Type