Genomics Associate Scientist

Functional Genomics · South San Francisco, California
Department Functional Genomics
Employment Type Contractor

The Opportunity

The heart of insitro’s strategy is the development of novel, cutting-edge methods in machine learning and high-throughput biology to address key bottlenecks in the drug development pipeline.  As a Genomics Associate Scientist, you will work to implement and execute genomic workflows, collaborating across multiple functions at insitro.  You will collaborate with scientists and engineers to develop, transfer and validate manual process steps to automated liquid handling and integrated systems. You will work to support efforts to improve the reproducibility and quality control tools on our high-throughput workflows. You will support the day-to-day activities for high-throughput molecular biology workflows ranging from RNA isolation to NGS-based QC.  In addition, you will support the development and operation of in-house sequencing and genomic assays, such as single cell and bulk RNA-seq. 

 

You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in the startup phase. Due to the early and exciting phase of growth, there are ample opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us and help make a difference to patients!


About You

  • B.S./M.S. in biological sciences, bio/chemical engineering, or similar experience
  • At least 1 year of relevant work experience in academia or industry
  • Experience with Molecular Biology techniques including NGS prep, and DNA and RNA purification 
  • Experience with mammalian cell culture 
  • Experience creating documentation for process validation and standardized operating procedures
  • Excellent communication and organizational skills 
  • Excellent analytical and problem-solving skills
  • Familiarity with liquid handling systems 
  • Experience managing external services for sample processing and QC


Nice to Have

  • Experience with single cell RNA-seq/perturb-seq, ATAC-seq
  • Experience with CRISPR screening
  • Experience working with automated NGS library prep methods


Benefits at insitro

  • Excellent medical, dental, and vision coverage
  • Team lunches (catered daily)
  • Commuter benefits


About insitro

insitro is a drug discovery and development company using machine learning and data generation at scale to transform the way that drugs are discovered and delivered to patients. We rely on human genetic cohorts, human-derived cellular disease models, and high-throughput biology and chemistry to identify coherent patient segments, actionable therapeutic targets, and new or existing chemical matter. The goal is to deliver predictive insights to improve the probability of success and reduce the number of costly dead ends along the R&D journey. The company has established enabling collaborations with Gilead in NASH and Bristol Myers Squibb in ALS and is building a pipeline of wholly owned and partnered medicines leveraging its unique insights on patient biomarkers, targets, and molecules. insitro is located in South San Francisco, CA and has raised over $600M from top tech, biotech, and crossover investors since formation in 2018. For more information on insitro, please visit the company’s website at www.insitro.com.


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  • Location
    South San Francisco, California
  • Department
    Functional Genomics
  • Employment Type
    Contractor