Associate Scientist II/III, Cell Line Engineering

High-Throughput Biology · South San Francisco, California
Department High-Throughput Biology
Employment Type Full-Time

The Opportunity

The heart of insitro’s strategy is the development of novel, cutting edge methods in machine learning and high-throughput biology to address key bottlenecks in the drug development pipeline.  You will work with a dynamic team to develop cutting edge molecular biology tools including CRISPRn/a/i, viral vectors, optical sequencing/biosensors, and vectors to generate iPSC cell lines to feed into insitro’s machine learning pipeline.  We are looking for motivated and talented candidates who are interested in being part of a unique, cross-disciplinary team of biologists, bioengineers, machine learners, and data scientists who want to make a difference. You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, yet is very much in formation providing many opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us and help make a difference to patients! 


About You

  • B.S./M.S. in a biological science, bio/chemical engineering, or equivalent 
  • 3+ years of relevant research experience
  • Extensive knowledge of cell culture and associated molecular biology assays  
  • Experience with human induced pluripotent stem cell culture (iPSC)
  • Interest in the design, plan and execution of cell engineering techniques
  • Excellent lab practice/organization, collaboration and communication required
  • Ability to adapt to multiple demands and changes
  • Passion for making a difference in the world


Nice to Have

  • Experience with CRISPRn/a/i and  and/or other cellular screening modalities
  • Experience with HDR knock-in/base editing for allelic editing
  • Experience developing high-throughput assays with a focus on scaling iPSC-biology
  • Experience with automation and high throughput assay development Familiarity with LIMS is a plus
  • Familiarity with Benchling or similar electronic laboratory notebook system


Benefits at insitro

  • Excellent medical, dental, and vision coverage
  • Open vacation policy
  • Team lunches (catered daily)
  • Commuter benefits
  • Paid parental leave


About insitro

insitro is a data-driven drug discovery and development company using machine learning and data generation at scale to transform the way that drugs are discovered and delivered to patients. insitro’s approach focuses on the development of predictive machine learning models to be brought to bear on key bottlenecks in pharmaceutical R&D. The company has established enabling collaborations with Gilead in NASH and Bristol Myers Squibb in ALS. insitro is located in South San Francisco, CA and has been supported by top tech, biotech, and crossover investors since formation in 2018. For more information on insitro, please visit the company’s website at www.insitro.com.


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  • Location
    South San Francisco, California
  • Department
    High-Throughput Biology
  • Employment Type
    Full-Time