Senior Automation Engineer

Process Engineering · South San Francisco, California
Department Process Engineering
Employment Type Full-Time

The Opportunity

The heart of insitro’s strategy is the development of novel, cutting-edge methods in machine learning and high-throughput biology to address key bottlenecks in the drug development pipeline.  As a Senior Automation Engineer, you will work to design, develop, and implement automation solutions for high-throughput biology protocols and workflows.  You will collaborate with scientists and automation engineers to develop, transfer and validate manual process steps to automated liquid handling and integrated systems.  You will work with system integrators on the design, implementation and support of high-throughput automated platforms.  You will also be responsible for assessing the efficiency and quality of operations to prioritize process improvements and optimizations.  In addition, you will help to mentor automation engineers with the implementation of a wide range of technologies, experiment designs and the use of systems engineering best practices.


You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in the startup phase. Due to the early and exciting phase of growth, there are ample opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us and help make a difference to patients!

About You

  • B.S, M.S, or Ph.D. in science, engineering discipline or equivalent experience
  • 5+ years of relevant work experience in academia or in industry
  • Significant experience in developing, optimizing and managing protocol methods on liquid handlers and integrated systems
  • Experience working with vendors to make modifications to existing software and hardware to enable expanded usage and new features for the multiple integrated systems
  • Demonstrated track record integrating assays and automation into efficient processes and workflows
  • Expertise in creating process diagrams, system requirements, technical specifications and engineering drawings
  • Experience in developing and optimizing new workflows in collaboration with scientists
  • Experience with integrating equipment data with LIMS tools
  • Excellent communication and organizational skills 
  • Excellent analytical and problem-solving skills
  • Familiarity with molecular biology and cell culture workflows 


Nice to Have

  • Competent programming methods on either Hamilton, Agilent and HRB liquid handlers
  • Competent using programming languages such as Python or C#
  • Experience working with automating high-throughput screening workflows
  • Experience working with automated iPSC cell culture systems

Benefits at insitro

  • Excellent medical, dental, and vision coverage
  • Open vacation policy
  • Team lunches (catered daily)
  • Commuter benefits
  • Paid parental leave

About insitro

insitro is a data-driven drug discovery and development company using machine learning and high-throughput biology to transform the way that drugs are discovered and delivered to patients. The company is applying state-of-the-art technologies from bioengineering to create massive data sets that enable the power of modern machine learning methods to be brought to bear on key bottlenecks in pharmaceutical R&D. The resulting predictive models are used to accelerate target selection, to design and develop effective therapeutics, and to inform clinical strategy. insitro was launched in 2018 with a Series A of $100M funded by top investors including a16z, Arch Venture Partners, Foresite Capital, GV, and Third Rock Ventures.

The company has announced collaborations with Gilead Sciences in the area of NASH (2019) and Bristol Myers Squibb in the area of ALS (2020) and, in mid 2020, completed a Series B financing of $143M including current investors and new investors Canada Pension Plan Investment Board (CPP Investments), T. Rowe Price, BlackRock, Casdin Capital and other leading investors. The company is located in South San Francisco, CA. For more information about insitro, please visit the company’s website at 

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  • Location
    South San Francisco, California
  • Department
    Process Engineering
  • Employment Type